Resident Evil 4 Remake Walkthrough: Complete Guide to 100% Completion, Separate Ways DLC, Mods & PC Requirements
This Resident Evil 4 remake walkthrough covers every chapter of Leon’s journey through the infected Spanish village. You get complete coverage of the Separate Ways DLC, where Ada Wong plays a pivotal role in the story. The guide also includes PC requirements, file size details for all platforms, and the best mods available for the game.
Whether you are a first-time player or a veteran of the original, this guide helps you achieve 100% completion. Every puzzle, boss fight, and collectible is covered in detail. The Separate Ways DLC walkthrough ensures you miss nothing from Ada’s campaign. Read on to conquer every challenge the remake throws at you.
Resident Evil 4 Remake Walkthrough At a Glance: Everything You Need to Know
| Category | Details | |
|---|---|---|
| Release Date | March 24, 2023 | |
| Developer | Capcom | |
| Platforms | PS4, PS5, Xbox Series X | S, PC (Steam) |
| Main Story Chapters | 16 | |
| Separate Ways Chapters | 7 | |
| PS5 File Size | 58.4 GB | |
| PS4 File Size | 26.99 GB | |
| **Xbox Series X | S File Size** | 67.18 GB |
| PC File Size | 40-60 GB | |
| PC Minimum CPU | Intel i5-7500 / AMD Ryzen 3 1200 | |
| PC Minimum RAM | 8 GB | |
| PC Minimum GPU | GTX 1050 Ti / RX 560 | |
| PC Recommended CPU | Intel i7-8700 / AMD Ryzen 5 3600 | |
| PC Recommended RAM | 16 GB | |
| PC Recommended GPU | GTX 1070 / RX 5700 |
Complete Chapter-by-Chapter Walkthrough
Resident Evil 4 Remake has 16 chapters total in the main story. The game is divided into three major areas: Village (Chapters 1-6), Castle (Chapters 7-12), and Island (Chapters 13-16).
Chapter 1 – The Village
Objective Summary: Follow the path and enter the lodge. Escape from the Hunter’s Lodge. Head for the Lake.
Walkthrough:
Start by following the trail until you reach the lodge. Enter the back of the lodge and watch the cutscene. Use the key to enter the basement and escape.
When you reach the Village Square, take the path on your left first. Be sneaky until you reach the house east of the village. Hug the north side of the village while crouched.
The Village Square Fight: You need to kill about 15 villagers to ring the bell manually. Alternatively, you can wait 4 minutes for the bell to ring automatically. Smash the barrel for some handgun ammo.
Dr. Salvador (Chainsaw Man) Strategy: Head to the two-story house near the top right of the village square. Entering this building triggers a cutscene with Leon blockading the door. Use the shotgun you find upstairs. Barricade the windows and push the ladder that leans against them. This temporarily prevents villagers from reaching the floor. Use grenades and headshots to take down Dr. Salvador.
Farm Area: After the Village Square, head to the Farm and Lakeside Settlement. Look for the first typewriter save point.
Key Items: Hunter’s Lodge Key, W-870 Shotgun (found in the Village Square house), Crude Charm file.
Blue Medallions: The first Blue Medallion Request is found in the Farm area. Pick up the request by the locked gate before tracking down the medallions.
Clockwork Castellan #1: Located in the Lakeside Settlement area, in a two-room shack near the middle of the area.
Estimated Completion Time: 45-60 minutes.
Chapter 2 – The Village (Continued)
Objective Summary: Head to the Church.
Walkthrough:
After the Lakeside Settlement, make your way toward the Church. You will encounter more Ganados along the path.
Key Items: Crystal Marble (for puzzle), Village Chief’s Manor key items.
Puzzle – Combination Lock: The combination lock in Chapter 2 requires a specific code.
Blue Medallions: Additional medallions appear in this chapter.
Clockwork Castellan #2: Located in the Village Chief’s Manor area.
Chapter 3 – The Lake
Walkthrough:
This chapter focuses on the lake area and the Del Lago boss fight.
Del Lago Boss Strategy: You fight Del Lago from a boat. Dodge pieces of driftwood and constantly hurl an unlimited amount of spears at the boss. The only real trick Del Lago has is disappearing under the water for a short while.
Key Items: Boat controls, various treasures around the lake.
Clockwork Castellan #3: Located near the Merchant at the dock/Quarry area.
Chapter 4 – The Church
Walkthrough:
Find the Key to the Church. Explore the boat dock area.
Church Insignia Key Puzzle: Find the Blasphemer Head and Apostate Head to create the church key.
El Gigante Boss Strategy: Dodge attacks and shoot the Plaga on his back.
Key Items: Church Key, Blasphemer Head, Apostate Head.
Clockwork Castellan #4: Located in this chapter’s area.
Chapter 5 – Village Finale
Walkthrough:
Continue through the village area. Face more challenging enemy encounters.
Clockwork Castellan #5: Located in the Village Leader’s Mansion.
Chapter 6 – Checkpoint and Chainsaw Sisters
Walkthrough: Progress through the Checkpoint and Slaughterhouse. Escape from the village.
Chainsaw Sisters Boss Strategy: Two chainsaw-wielding enemies. Use the environment to separate them. Focus on one at a time.
Key Items: Various weapons and treasures.
Chapter 7 – Castle Entrance
Walkthrough: Enter the Castle area. This marks the beginning of the Castle section (Chapters 7-12).
Treasures: Vintage Compass can be collected in Chapter 7.
Sword Puzzle: Place the swords in the reliefs from left to right: Iron Sword, Golden Sword, Bloodied Sword, Rusted Sword.
Clockwork Castellan #7: Located in the Castle area.
Chapter 8 – Castle Depths
Walkthrough: Navigate through the Castle’s deeper sections.
Crimson Lantern Puzzle: Pick up Lithographic Stones B and C. Defeat the Armored El Gigante.
Sun and Moon Switches: You can skip the sun and moon switches and doors in Chapter 8. A section will require you to pull switches marked with sun and moon icons.
Treasures: Gold Bar can be collected in Chapter 8.
Clockwork Castellan #8: Located at the Castle Battlements.
Chapter 9 – Grand Hall
Walkthrough: Explore the Courtyard, Grand Hall, Armory, and Dining Hall. Head for the Ballroom.
Headless Statue Puzzle (Chimera Puzzle): Find and use the Serpent, Lion, and Goat Heads on the headless chimera in the Grand Hall.
Library Clock Puzzle: The solution varies by difficulty. In Assisted and Standard mode, the solution is “11:04”. In Hardcore and Professional mode, the note reads “VIIXII”.
Treasures: Various treasures in the Treasury area.
Clockwork Castellan #10: Located in the Ballroom.
Chapter 10 – Verdugo
Walkthrough: Face the Verdugo boss.
Verdugo Boss Strategy: Freeze Verdugo with liquid nitrogen. Attack while frozen.
Chapter 11 – Mines and Hive
Walkthrough: Navigate through the Mines, Hive, and Blast Furnace.
Clockwork Castellan #11: Located at the Mines Stopover.
Chapter 12 – Clock Tower
Walkthrough: Climb the Clock Tower and reach the Ancient Chantry.
Clock Tower Mechanics: Use gears and cranks to progress.
Ramón Salazar Boss Strategy: Shoot his weak points. Use the golden egg for massive damage.
Chapter 13 – The Island
Walkthrough: Arrive at the Island. Navigate through the Wharf and Incubation Lab.
Treasures: Pearl Bangle can be obtained during Chapter 13.
Clockwork Castellan #13: Located at the Campsite.
Chapter 14 – Cargo Depot
Walkthrough: Progress through the Cargo Depot and Ruins.
Jack Krauser Boss Strategy: Use parry against knife attacks. Use shotgun or high-damage weapons between parries. The Broken Butterfly Magnum is the best weapon to hit Krauser with while he’s unguarded. Stay behind cover and wait for Krauser to shoot.
Clockwork Castellan #14: Located at the Campsite.
Chapter 15 – Summit
Walkthrough: Continue toward the summit. Navigate through the Stronghold, Bulwark Gate, Cliffside Ruins, and Specimen Storage.
Clockwork Castellan #15: Located in Specimen Storage.
Chapter 16 – Final Chapter
Walkthrough: Start in Luis’s Laboratory. Exit the lab and boost Ashley up onto the upper platform on the left. Wait for her to drop down the ladder. Climb up and walk onto the bridge. Progress through the chapter until you reach the Sanctuary.
Osmund Saddler Boss Strategy:
- Phase 1: Take out his eyes, then run up and knife his head.
- Keep moving down the linear path of the arena.
- Keep shooting at the gold orb.
- Lure him to the canisters and explode them. This stuns him briefly.
- Use the rocket launcher if available.
Clockwork Castellan #16: Located in the Underground Passage during the countdown.
Treasures: Four treasures in Chapter 16.
All Boss Fight Strategies
| Boss | Chapter | Strategy | Weakness |
|---|---|---|---|
| Dr. Salvador | 1 | Barricade windows, use shotgun, grenades | Headshots |
| Del Lago | 3 | Dodge driftwood, throw spears when charging | Mouth |
| El Gigante | 4 | Dodge attacks, shoot Plaga on back | Back/Plaga |
| Bitores Méndez | 6 | Get to high ground, shoot barrels, expose Plaga | Plaga/Explosives |
| Verdugo | 10 | Freeze with liquid nitrogen | Frozen state |
| Ramón Salazar | 12 | Shoot weak points, use golden egg | Golden egg |
| Jack Krauser | 14 | Parry knife attacks, use shotgun/magnum | Knife fight/QTE |
| Osmund Saddler | 16 | Shoot eyes, knife head, use rocket launcher | Rocket launcher |
All Collectibles Guide
16 Clockwork Castellans
| # | Chapter | Location |
|---|---|---|
| 1 | Chapter 1 | Lakeside Settlement – two-room shack |
| 2 | Chapter 2 | Village Chief’s Manor |
| 3 | Chapter 3 | Merchant shop docks/Quarry |
| 4 | Chapter 4 | Various |
| 5 | Chapter 5 | Village Leader’s Mansion |
| 6 | Chapter 6 | After cabin fight |
| 7 | Chapter 7 | Castle area |
| 8 | Chapter 8 | Castle Battlements |
| 9 | Chapter 9 | Various |
| 10 | Chapter 10 | Ballroom |
| 11 | Chapter 11 | Mines Stopover |
| 12 | Chapter 12 | Various |
| 13 | Chapter 13 | Campsite |
| 14 | Chapter 14 | Campsite |
| 15 | Chapter 15 | Specimen Storage |
| 16 | Chapter 16 | Underground Passage during countdown |
All Blue Medallions
Blue Medallions are found in the Farm, Quarry, Castle Gate, Grand Hall, Castle Depot, and Cliffside Ruins. Pick up the relevant request poster and it will mark every Blue Medallion location on your map.
Farm Medallions (5): Behind the hut with the typewriter, in barn stalls, on the ceiling of the barn beside the small windmill, behind the Wayshrine.
Quarry and Fish Farm Medallions: Additional medallions in these areas.
Castle Gate Medallions: Found after leaving the Village.
Reward: Destroying all medallions in a group rewards Spinels.
All Treasures (100+)
There are 104 Treasures scattered throughout the Village, Castle, and Island regions. Purchase the Treasure Map from the Merchant for 3 Spinels to reveal locations.
Treasure Types:
- Velvet Blue (Base Selling Price: 2,500)
- Pearl Pendant
- Brass Pocket Watch
- Red Gemstone Ring
- Ornate Necklace
- Ruby
- Emerald
- Sapphire
- Alexandrite
Gem Combinations: Combining gems with treasures increases their value.
All Small Keys (8)
Small Keys unlock locked drawers throughout the game. Each key opens one drawer.
All Files
Files provide story and lore context. Collect all for 100% completion.
All Merchant Requests
Merchant Requests reward Spinels and Pesetas. Complete all requests for maximum rewards.
All Puzzle Solutions
| Puzzle | Chapter | Solution |
|---|---|---|
| Combination Lock | 2 | Specific code |
| Crystal Marble | 2 | Rotate pellets until it matches the insignia |
| Church Insignia Key | 4 | Find Blasphemer + Apostate Heads |
| Sword Puzzle | 7 | Iron, Golden, Bloodied, Rusted (left to right) |
| Lithograph Puzzle | 8 | Matching symbols |
| Sun and Moon Switches | 8 | Pull in correct sequence |
| Headless Statue (Chimera) | 9 | Serpent, Lion, Goat Heads |
| Library Clock | 9 | Assisted/Standard: 11:04; Hardcore/Professional: VIIXII |
| Hexagon Puzzle | Various | Rotate groups to form circle |
| Clock Tower | 12 | Gear and crank mechanics |
| Treasury Gate | Various | Symbol combinations |
Separate Ways DLC Complete Walkthrough
Separate Ways is a DLC adventure that covers Ada Wong’s journey while it runs concurrently with Leon’s.
How Many Chapters?
There are 7 Chapters in the Separate Ways DLC. In the original Separate Ways DLC, there were only 5 Chapters. The inclusion of new travel mechanics added 2 extra chapters.
Chapter 1 Walkthrough
After rescuing Luis inside the castle prison, use your grappling hook to find your way out of the castle and head back to the village.
Objectives:
- Escape from the Dungeons
- Fight the Black Robe
- Head for the Exit
- Escape from the Castle
Chapter 2 Walkthrough
After escaping the Black Robe in the Castle, Ada must rendezvous with their asset at the Village. Traverse back from the mountain cliffs to reach the Church.
Objectives:
- Head for the Church
- Go through the Village Square
- Head for the Village Chief’s manor
Puzzle – Cliffside Door: Press the right buttons on the dial to unlock.
Chapter 3 Walkthrough
Reunite with Luis at the big house past the windmill after helping Leon from Mendez.
Objectives:
- Find clues on Luis’s whereabouts
- Head for the Abandoned Factory
- Enter the Abandoned Factory
- Leave the Abandoned Factory
- Head for the Villa
Chapter 4 Walkthrough
Explore the Castle and look for the ingredients needed to make a cure while Luis is looking for the Amber.
Objectives:
- Find the Cure with Luis
- Search for the Red Ink
- Search for the Gold Bottle
- Search for the Blue Butterfly
Puzzles:
- Lithographic Stone Door: Swap the four stones to match damaged images
- Stone Tablet Door Lock
- Shield Puzzle: Shoot bottom-left, then top-right, then bottom-right shields
Chapter 5 Walkthrough
Reunite with Luis, only to find that Krauser has stolen the Amber. Group up with Leon as you follow Krauser onto the island.
Objectives:
- Use Iris to Track Luis
Boss – U-3 (Pesanta): The first major boss fight in Separate Ways.
Chapter 6 Walkthrough
Continue the pursuit on the island.
Puzzle – Comms Facility Locks
Chapter 7 Walkthrough
Complete the Separate Ways story.
Separate Ways Collectibles
All Separate Ways Files: Various files including Villager’s Diary, Clemente’s Appeal, Cell for Awaiting Judgement, Photo of Ashley, Unknown Numbers, Scrawled Orders, and Suppressant Ingredients.
Separate Ways Merchant Requests: 7 total. Complete all seven Merchant Requests to unlock the indestructible Elite Knife.
All Separate Ways Treasures: Various treasures throughout the DLC.
Best Weapons Guide
| Weapon | Location | Cost | Best Upgrades |
|---|---|---|---|
| SG-09 R | Starting pistol | Free | Damage first |
| W-870 | Village Square | Free | Damage |
| Red9 | Lake | Purchase | Damage + Stock |
| TMP | Merchant | Purchase | Stability |
| Broken Butterfly | Merchant | Purchase | Damage |
| Killer7 | Merchant | Purchase | Damage |
| Chicago Sweeper | NG+ | Unlock | Infinite ammo |
| Infinite Rocket Launcher | NG+ | Unlock | N/A |
Weapon Tips:
- Upgrade damage first on all weapons
- The Red9 is considered one of the best pistols
- Save magnum ammo for boss fights
- The Chicago Sweeper with infinite ammo makes Professional mode much easier
Advanced Combat Mechanics Guide
Parry System
The parry system is new to the remake. Time your knife blocks perfectly to parry enemy attacks.
Timing Windows: Different enemy types have different attack speeds. Practice timing against basic Ganados first.
Knife Durability Management: Knives now have durability. They break after repeated use. Repair at the Merchant.
Perfect Parry vs Regular Parry: Perfect parries stagger enemies and open them for melee attacks.
Melee Combos
Stun + Melee Prompt: Shoot enemies in the knee or head to stun them. Run up and press the melee button.
Suplex: Perform from behind stunned enemies.
Knife Finishers: Use the knife on downed enemies to conserve ammo.
Stealth Tactics
Crouch walking allows you to move silently. Take out a few villagers without alerting them.
Silent Knife Kills: Approach enemies from behind while crouched.
Enemy Alert Mechanics: Once enemies are alerted, stealth is no longer possible in that area.
Ammo Conservation
Knee Shots + Melee: Shoot enemies in the knee, then use melee attacks. This saves ammo.
Environmental Kills: Shoot lanterns to drop them on enemies. Explode barrels near groups.
Headshot Prioritization: Headshots deal more damage and conserve ammo.
Resource Management: Stockpile handgun ammo and herbs early.
PC Requirements & Performance Guide
Minimum Requirements
| Component | Minimum |
|---|---|
| OS | Windows 10 (64-bit) |
| Processor | Intel i5-7500 / AMD Ryzen 3 1200 |
| Memory | 8 GB RAM |
| Graphics | NVIDIA GTX 1050 Ti 4GB / AMD RX 560 4GB |
| DirectX | Version 12 |
| Storage | 40 GB available space |
Performance Expectation: 45 FPS at 1080p.
Recommended Requirements
| Component | Recommended |
|---|---|
| OS | Windows 10/11 (64-bit) |
| Processor | Intel i7-8700 / AMD Ryzen 5 3600 |
| Memory | 16 GB RAM |
| Graphics | NVIDIA GTX 1070 / AMD RX 5700 |
| Storage | 50+ GB SSD recommended |
Performance Expectation: 60 FPS at 1080p.
Ray Tracing Requirements
For ray tracing, you need an AMD RX 6700 XT or NVIDIA RTX 2070.
Performance Tips
SSD vs HDD: Install on SSD for faster load times.
VRAM Usage: 3GB for high textures.
Graphics Settings: Adjust settings based on your GPU. Lower shadows and reflections for better performance.
Driver Updates: Update your graphics card drivers to minimize errors.
File Size by Platform
| Platform | File Size | |
|---|---|---|
| PlayStation 5 | 58.4 GB | |
| PlayStation 4 | 26.99 GB | |
| Xbox Series X | S | 67.18 GB |
| PC (Steam) | 40-60 GB |
Note: These sizes are without the day-one patch.
Best Mods for Resident Evil 4 Remake
Multiplayer/Co-op Mod
Creator: claybtv
Platform: Nexus Mods
Size: ~144.86 MB
Features: Syncs two copies of the game in real-time. Includes all doors, story events, enemies, switches, alarms, and other elements.
Status: Beta
Known Issues: Lag spikes, enemy synchronization bugs, auto-pausing when inventory is opened. No way to open inventory without pausing for co-op partners.
Updates: First update released June 15, repairing server crash issues.
Future Plans: LAN multiplayer version in development.
Character Selection: Choose from a roster of RE4 characters so you don’t have two Leons.
Download: Free via Nexus Mods.
Tactical First-Person Mode
Features: First-person camera, iron sights, custom aim stances.
Requirements: REFramework + _ScriptCore
Platform: Nexus Mods
Cost: Free
Berserker Mod
Creator: RabbitTooneedIM
Features: Remixed extra mode similar to RE3 Nightmare. Increased difficulty for replay value.
4K 60 FPS Remastered FMVs
Size: ~2.2GB
Installation: HDD installation recommended
Other Notable Mods
- New melee animations for Leon
- Auto-pickup option for items
- First aid spray replacement mods
Original vs Remake: Key Differences
Chapter Structure: Separate Ways expanded from 5 to 7 chapters.
Plot and Character Development: Updated story elements and deeper character backstories.
New Gameplay Mechanics: Parry system, stealth, and knife durability.
Graphics: RE Engine provides modern visuals.
Boss Fight Mechanics: Changed boss fight patterns and strategies.
Merchant System: Expanded with new requests and rewards.
New Collectibles: Clockwork Castellans added as new collectible type.
Controls: Updated for modern gaming standards.
No QTEs: Quick Time Events removed.
Tips for S+ Rank and 100% Completion
S+ Rank Requirements
| Difficulty | Time Limit | Save Limit |
|---|---|---|
| Assisted | 4:00:00 | – |
| Standard | 5:00:00 | – |
| Hardcore | 5:30:00 | – |
| Professional | 5:30:00 | 15 saves |
S+ Rank Rules
- Cannot be earned in New Game Plus
- Must be on a New Game
- No special weapons allowed
- Saving more than 15 times prevents S+ Rank on Professional
S+ Rank Tips
Save Management: Plan your saves strategically. Only save before difficult sections.
Weapon Upgrade Priority: Focus on upgrading one or two weapons fully.
Chapter Skips: Skip optional content when possible.
Time Management: Keep moving. Don’t backtrack unnecessarily.
NG+ Unlockables: Complete the game once to unlock powerful weapons for subsequent playthroughs.
100% Completion
- Collect all 16 Clockwork Castellans
- Destroy all Blue Medallions
- Find all 104 Treasures
- Complete all Merchant Requests
- Find all Files
- Unlock all weapons
- Achieve S+ Rank on all difficulties
Frequently Asked Questions
How long does it take to beat RE4 Remake?
The main story takes approximately 15-20 hours for a first playthrough. 100% completion takes 30-40 hours.
Does the demo progress carry over?
Yes, progress from the Chainsaw Demo carries over to the full game.
Is Separate Ways worth it?
Yes. It adds 7 new chapters with Ada Wong as the protagonist, new mechanics, and new story content.
Can I play co-op?
Officially, no. But a co-op mod by claybtv allows two players to play together.
What’s the best weapon?
The Red9 is considered one of the best pistols. The Chicago Sweeper with infinite ammo is powerful in NG+. The Infinite Rocket Launcher is the ultimate weapon.
What are the PC requirements?
Minimum: i5-7500/Ryzen 3 1200, 8GB RAM, GTX 1050 Ti/RX 560. Recommended: i7-8700/Ryzen 5 3600, 16GB RAM, GTX 1070/RX 5700.
How big is the game?
PS5: 58.4GB, PS4: 26.99GB, Xbox: 67.18GB, PC: 40-60GB.
Can I skip the Village Square fight?
You can either kill about 15 villagers or wait 4 minutes for the bell to ring automatically.
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